MR

Merck & Co., Inc. stock research

Dec 31, 2025

FY2025 Q4

Merck & (MRK) Gross Margin — Quarter Ended Dec 31, 2025

Revenue decreased compared to the prior quarter, while cost of revenue increased, causing gross profit to decline and gross margin to weaken. Versus the same quarter last year, revenue was higher but cost of revenue rose more sharply, resulting in lower gross profit and a weakened gross margin.

Gross margin takeaway

Quarter ended Dec 31, 2025 · FY2025 Q4

Revenue decreased compared to the prior quarter, while cost of revenue increased, causing gross profit to decline and gross margin to weaken. Versus the same quarter last year, revenue was higher but cost of revenue rose more sharply, resulting in lower gross profit and a weakened gross margin.

  • The most observable driver of the gross margin change is the relationship between revenue and cost of revenue: revenue fell while cost of revenue rose sequentially, compressing margin. Year-over-year, revenue growth was outpaced by cost growth, also pressuring margin.
  • Compared to the immediately preceding quarter, gross margin weakened as revenue was lower and cost of revenue was higher. Compared to the same quarter one year earlier, gross margin also weakened, with revenue higher but cost of revenue substantially higher.

Gross margin snapshot

The selected quarter's reported revenue, gross profit, direct costs, and margin comparisons.

Gross margin

66.2%

Gross profit

$10.8B

Revenue

$16.4B

Cost of revenue

$5.6B

Quarter-over-quarter change

-11.5 pts

Year-over-year change

-9.3 pts

Quarterly gross margin trend

A four-quarter view of the revenue and direct-cost bridge behind gross margin.

PeriodRevenueGross profitCost of revenueGross margin
Mar 31, 2025$15.5B$12.1B$3.4B78.0%
Jun 30, 2025$15.8B$12.2B$3.6B77.5%
Sep 30, 2025$17.3B$13.4B$3.9B77.7%
Dec 31, 2025$16.4B$10.8B$5.6B66.2%

Quarterly comparisons

Compare the selected margin with the preceding quarter and the same fiscal quarter one year earlier.

Previous-quarter change

Sep 30, 2025

-11.5 pts

Year-over-year change

Dec 31, 2024

-9.3 pts

What the margin says

Filing-constrained interpretation of margin direction, comparisons, and what to monitor next.

The most observable driver of the gross margin change is the relationship between revenue and cost of revenue: revenue fell while cost of revenue rose sequentially, compressing margin. Year-over-year, revenue growth was outpaced by cost growth, also pressuring margin.

Compared to the immediately preceding quarter, gross margin weakened as revenue was lower and cost of revenue was higher. Compared to the same quarter one year earlier, gross margin also weakened, with revenue higher but cost of revenue substantially higher.

Monitor the trajectory of cost of revenue relative to revenue, as its increase in both comparisons was the primary factor behind margin compression.

MRK Gross Margin — Quarter Ended Dec 31, 2025