VR

Vertex Pharmaceuticals Incorporated stock research

Sep 30, 2025

FY2025 Q3

Vertex Pharmaceuticals (VRTX) Gross Margin — Quarter Ended Sep 30, 2025

Revenue increased compared to both the prior quarter and the same quarter last year, while cost of revenue also rose. Gross profit expanded at a slightly faster rate than revenue, resulting in a modest improvement in gross margin.

Gross margin takeaway

Quarter ended Sep 30, 2025 · FY2025 Q3

Revenue increased compared to both the prior quarter and the same quarter last year, while cost of revenue also rose. Gross profit expanded at a slightly faster rate than revenue, resulting in a modest improvement in gross margin.

  • Gross margin improved relative to both comparison periods, supported by gross profit growth that outpaced revenue growth.
  • Compared to the immediately preceding quarter, gross margin was slightly higher. Versus the same quarter one year earlier, gross margin was also higher.

Gross margin snapshot

The selected quarter's reported revenue, gross profit, direct costs, and margin comparisons.

Gross margin

86.5%

Gross profit

$2.7B

Revenue

$3.1B

Cost of revenue

$414.8M

Quarter-over-quarter change

+0.3 pts

Year-over-year change

+0.7 pts

Quarterly gross margin trend

A four-quarter view of the revenue and direct-cost bridge behind gross margin.

PeriodRevenueGross profitCost of revenueGross margin
Dec 31, 2024$2.9B$2.5B$423.4M85.5%
Mar 31, 2025$2.8B$2.4B$363.0M86.9%
Jun 30, 2025$3.0B$2.6B$407.5M86.3%
Sep 30, 2025$3.1B$2.7B$414.8M86.5%

Quarterly comparisons

Compare the selected margin with the preceding quarter and the same fiscal quarter one year earlier.

Previous-quarter change

Jun 30, 2025

+0.3 pts

Year-over-year change

Sep 30, 2024

+0.7 pts

What the margin says

Filing-constrained interpretation of margin direction, comparisons, and what to monitor next.

Gross margin improved relative to both comparison periods, supported by gross profit growth that outpaced revenue growth.

Compared to the immediately preceding quarter, gross margin was slightly higher. Versus the same quarter one year earlier, gross margin was also higher.

Monitor the trajectory of cost of revenue relative to revenue, as its increase has accompanied revenue growth.